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Chimeric antigen receptor T-cell (CAR-T) therapy is a new type of cancer treatment that may be used to treat B-cell acute lymphoblastic leukaemia and diffuse large B-cell lymphoma (DLBCL). This booklet explains how CAR-T therapy works and who may currently receive it, and describes the possible side-effects. It also discusses the likely future for CAR-T therapy and the clinical trials currently taking place in the UK. It includes a glossary of terms and details of further information and support.
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